| Diphenhydramine |
Mechanism of Action
Diphenhydramine (Benadryl) is an antihistamine used to prevent the physiological
actions of histamine in the body. After contact with a allergin, histamines reach
H1- and H2-receptor sites. While providing only symptomatic relief,
Diphenhydramine is to be used in conjuction with epinephrine.
Indications
Severe anaphylaxis
To be given in conjunction with epinephrine
Packaging
50 mg in 1 ml (vial)
Drug box inventory = 1
Onset & Duration
Onset: 1-3 hours for maximum effect.
Duration: 6-12 hours
Doses and Administration
1 mg/kg
50 mg (1 ml) slow IV or IM
Precautions
May cause:
Drowsiness and/or sedation
Hypotension
Palpitations
Tachycardia
Pediatrics
Same doses as an adult (refer to medical control)
Diphenhydramine (Benadryl) is an antihistamine used to prevent the physiological
actions of histamine in the body. After contact with a allergin, histamines reach
H1- and H2-receptor sites. While providing only symptomatic relief,
Diphenhydramine is to be used in conjuction with epinephrine.
Indications
Severe anaphylaxis
To be given in conjunction with epinephrine
Packaging
50 mg in 1 ml (vial)
Drug box inventory = 1
Onset & Duration
Onset: 1-3 hours for maximum effect.
Duration: 6-12 hours
Doses and Administration
1 mg/kg
50 mg (1 ml) slow IV or IM
Precautions
May cause:
Drowsiness and/or sedation
Hypotension
Palpitations
Tachycardia
Pediatrics
Same doses as an adult (refer to medical control)
