| Midazolam |
Mechanism of Action
Short acting benzodiazepine.
CNS depressant with sedative, muscle relaxant, anticonvulsant, and
amnesiac effects.
Estimated to be 3-4 times as potent as diazepam.
Intensifies activity of gamma-aminobenzoic acid, a major inhibitory
neurotransmitter of the brain. This acts to calm the patient, relaxes skeletal
muscles, blocks memory, prevents feeling pain, but enables them to follow
commands
Indications
To be considered in the patient needing immediate cardioversion
Packaging
10 mg in 2 ml (vial)
Drug box inventory = 2
Onset & Duration
Onset: 1-5 min
Duration: less than 2 hours
Doses and Administration
Give 2-4 mg IV bolus slow IVP
For Chemical Restraint:
10 mg MAD
5 mg IM
Precautions
Do not use in:
Obstetrics
Coma
Shock
Acute alcohol intoxication where vital signs are depressed.
Watch for respiratory depression
Pediatrics
Dose: Versed 0.1 mg/kg IV/IO (over 1-2 min) (max dose 4 mg)
Could be considered in the violent patient
Short acting benzodiazepine.
CNS depressant with sedative, muscle relaxant, anticonvulsant, and
amnesiac effects.
Estimated to be 3-4 times as potent as diazepam.
Intensifies activity of gamma-aminobenzoic acid, a major inhibitory
neurotransmitter of the brain. This acts to calm the patient, relaxes skeletal
muscles, blocks memory, prevents feeling pain, but enables them to follow
commands
Indications
To be considered in the patient needing immediate cardioversion
Packaging
10 mg in 2 ml (vial)
Drug box inventory = 2
Onset & Duration
Onset: 1-5 min
Duration: less than 2 hours
Doses and Administration
Give 2-4 mg IV bolus slow IVP
For Chemical Restraint:
10 mg MAD
5 mg IM
Precautions
Do not use in:
Obstetrics
Coma
Shock
Acute alcohol intoxication where vital signs are depressed.
Watch for respiratory depression
Pediatrics
Dose: Versed 0.1 mg/kg IV/IO (over 1-2 min) (max dose 4 mg)
Could be considered in the violent patient
