Naloxone
NALOXONE
(Narcan)
PACKAGED: 2 mg in 2 ml vial, 1 mg/ml (2 in drug bag)


NOTE: Naloxone administration should be to improve respirations in an unresponsive
patient with a
hypoventilation condition and not to awaken an unconscious patient. It
should be given slowly. Narcan
can precipitate narcotic withdrawal with all of its
problems. If the patient has a pulse, Naloxone should be
given before intubation. Once
Naloxone is administered, the patient must be removed by EMS.


INDICATIONS:
Respirations depressed or high index of suspicion of narcotic overdose
Suspicion of drug abuse in cardiac arrest


ADULT:
2 mg slow IV, IM, IO, SQ, ETT if IV unsuccessful. Titrate to adequate respirations.
or {2 mg intranasally {IN} using MAD}
If respirations don’t improve after 3 minutes, establish IV and administer slow IV dose.
Repeat doses may
be given.

PEDI:
Naloxone:
≤ 20 kg 0.1 mg/kg slow IV/IN/IM/SQ/IO/ETT (Max Dose 2 mg) may repeat x one
> 20 kg 2 mg, slow IV/IN/IM/SQ/IO/ETT, may repeat x one
Naloxone slow IV is preferred, but it may be given IN before IV is established.
Titrate to adequate respirations.
If using IN route, if respirations don’t improve after 3 minutes, establish IV and administer
IV
dose.

THERAPEUTIC ACTION:
A competitive narcotic antagonist

CONTRAINDICATIONS:
Hypersensitivity
Use with caution in narcotic-dependent patients who may experience withdrawal
syndrome (including
neonates of narcotic-dependent mothers).

PRECAUTIONS AND SIDE EFFECTS:
Tachycardia, hypertension, dysrhythmias, nausea and vomiting, diaphoresis, blurred
vision, opiate
withdrawal
May not reverse hypotension
Caution should be exercised when administering to narcotic addicts (may precipitate
withdrawal with
hypertension, tachycardia and combative behavior).

REQUIRES MCP:
ADULT: No
PEDI: No