
NALOXONE
(Narcan)
PACKAGED: 2 mg in 2 ml vial, 1 mg/ml (2 in drug bag)
NOTE: Naloxone administration should be to improve respirations in an unresponsive
patient with a hypoventilation condition and not to awaken an unconscious patient. It
should be given slowly. Narcan can precipitate narcotic withdrawal with all of its
problems. If the patient has a pulse, Naloxone should be given before intubation. Once
Naloxone is administered, the patient must be removed by EMS.
INDICATIONS:
Respirations depressed or high index of suspicion of narcotic overdose
Suspicion of drug abuse in cardiac arrest
ADULT:
2 mg slow IV, IM, IO, SQ, ETT if IV unsuccessful. Titrate to adequate respirations.
or {2 mg intranasally {IN} using MAD}
If respirations don’t improve after 3 minutes, establish IV and administer slow IV dose.
Repeat doses may be given.
PEDI:
Naloxone:
≤ 20 kg 0.1 mg/kg slow IV/IN/IM/SQ/IO/ETT (Max Dose 2 mg) may repeat x one
> 20 kg 2 mg, slow IV/IN/IM/SQ/IO/ETT, may repeat x one
Naloxone slow IV is preferred, but it may be given IN before IV is established.
Titrate to adequate respirations.
If using IN route, if respirations don’t improve after 3 minutes, establish IV and administer
IV dose.
THERAPEUTIC ACTION:
A competitive narcotic antagonist
CONTRAINDICATIONS:
Hypersensitivity
Use with caution in narcotic-dependent patients who may experience withdrawal
syndrome (including neonates of narcotic-dependent mothers).
PRECAUTIONS AND SIDE EFFECTS:
Tachycardia, hypertension, dysrhythmias, nausea and vomiting, diaphoresis, blurred
vision, opiate withdrawal
May not reverse hypotension
Caution should be exercised when administering to narcotic addicts (may precipitate
withdrawal with hypertension, tachycardia and combative behavior).
REQUIRES MCP:
ADULT: No
PEDI: No
